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Elevated Risk of Overweight/Obesity-Related Markers and Low Muscular Fitness in Children Attending Public Schools in Chile
(International Journal of Environmental Research and Public Health, 2022)In Chile, children of low socioeconomic status usually attend public schools and have few opportunities to engage in healthy behaviors. This may increase their risk of overweight/obesity and low muscular fitness. Therefore, ... -
Work/household, transport, and leisure domains account for the sex gap in physical activity in Chile
(Frontiers in Public Health, 2022) -
Exploring the sequential accumulation of metabolic syndrome components in adults
(Scientific Reports, 2022) -
¿Los niveles de Testosterona y Cortisol influyen en el rendimiento en el rugby? Una mirada al rugby sevens.
(2022-04-30)Resumen: Introducción: El Rugby 7 (R7) es una rama del Rugby Unión (RU) y se caracteriza principalmente por ser un deporte de oposición con períodos de juego intensos y de corta duración, por lo tanto, los componentes ... -
Severe COVID-19 correlates with lower mitochondrial cristae density in PBMCs and greater sitting time in humans
(2022-05-27)An interaction between mitochondrial dynamics, physical activity levels, andCOVID-19 severity has been previously hypothesized. However, this has notbeen tested. We aimed to compare mitochondrial morphology and cristae ... -
Predictive equations for energy expenditure in adult humans: From resting to free-living conditions
(Wiley, 2022)Humans acquire energy from the environment for survival. A central question for nutritional sciences is how much energy is required to sustain cellular work while maintaining an adequate body mass. Because human energy ... -
Effect of supervised resistance training on arm volume, quality of life and physical perfomance among women at high risk for breast cancer-related Lymphedema: A study protocol for a randomized controlled Trial (STRONG-B)
(Frontiers Media, 2022-03)Objectives: To determine the preventive effects of supervised resistance training on arms volume, quality of life, physical performance, and handgrip strength in Chilean women at high risk for breast cancer-related ... -
A mutation in desmin makes skeletal muscle less vulnerable to acute muscle damage after eccentric loading in rats
(Wiley Open Access, 2021-09-01)Desminopathy is the most common intermediate filament disease in humans. The most frequent mutation causing desminopathy in patients is a R350P DES missense mutation. We have developed a rat model with an analogous mutation ... -
Microencapsulated pomegranate peel extract induces mitochondrial complex IV activity and prevents mitochondrial cristae alteration in brown adipose tissue in mice fed on a high-fat diet
(Cambridge University Press, 2021-09-28)Pomegranate peel is an agro-industrial residue obtained after fruit processing with high total polyphenol (TP) content, making it an attractive by-product for its reuse. Pomegranate peel extract (PPE) and its bioactive ... -
The fasting-feeding metabolic transition regulates mitochondrial dynamics
(Federation of American Society of Experimental Biology (FASEB), 2021-10-10)In humans, insulin resistance has been linked to an impaired metabolic transition from fasting to feeding (metabolic flexibility; MetFlex). Previous studies suggest that mitochondrial dynamics response is a putative ... -
Low abundance of Mfn2 protein correlates with reduced mitochondria-SR juxtaposition and mitochondrial cristae density in human men skeletal muscle: Examining organelle measurements from TEM images
(Wiley Open Access, 2021-04-04)The role of mitofusin 2 (Mfn2) in the regulation of skeletal muscle (SM) mitochondria-sarcoplasmic (SR) juxtaposition, mitochondrial morphology, mitochondrial cristae density (MCD), and SM quality has not been studied in ... -
Association between adipose tissue characteristics and metabolic flexibility in humans: A systematic review
(Frontiers Media, 2021-12-03)Adipose tissue total amount, distribution, and phenotype influence metabolic health. This may be partially mediated by the metabolic effects that these adipose tissue characteristics exert on the nearby and distant ... -
Similar metabolic health in overweight/obese individuals with contrasting metabolic flexibility to an oral glucose tolerance test
(Frontiers Media, 2021-11-16)Background: Low metabolic flexibility (MetF) may be an underlying factor for metabolic health impairment. Individuals with low MetF are thus expected to have worse metabolic health than subjects with high MetF. Therefore, ...