Repositorio Institucional
Sistema de Bibliotecas Universidad Finis Terrae
El Repositorio Institucional de la Universidad FinisTerrae, es gestionado por el Sistema de Bibliotecas y tiene por objetivo permitir el acceso libre a la producción académica e institucional de la Universidad, aumentando la visibilidad de sus contenidos y garantizando su conservación.
Envíos recientes
Mitochondria across the globe: dive rse voices, shared energy
(Elsevier, 2026-06) Castro-Sepúlveda, Mauricio; Hevener, Andrea; Joensuu, Merja; Qiu, Jian; Ryan, Dylan G.
Like mitochondria themselves, research on this organelle can take many shapes and sizes. This month, to coincide with the Cell Press Symposia: Multifaceted Mitochondria, we are highlighting the diversity of the global mitochondria community with contributions from researchers at all career stages, published across Cell Metabolism, Molecular Cell, Cell Reports, and Trends in Endocrinology and Metabolism. Together, these voices showcase the central role of mitochondrial research in metabolism, inflammation, cell biology, and much more.
Capítulo 3: Conceptos básicos de genética y epigenética
(Ediciones UC, 2026-04) Carvajal, Cristian; Tapia-Castillo, Alejandra; Fardella, Carlos
Endocrinología Clínica es hoy un manual imprescindible para la formación y el ejercicio de la endocrinología en Chile y Latinoamérica. Tras el éxito de sus versiones anteriores, esta tercera edición surge como respuesta a los acelerados avances diagnósticos y terapéuticos que han transformado el cuidado de las enfermedades hormonales. Con un enfoque docente, claro y orientado a la resolución de problemas clínicos, el libro reúne a destacados especialistas nacionales e internacionales y aborda de manera integral las principales áreas de la disciplina, desde patología tiroidea y diabetes hasta neuroendocrinología, metabolismo óseo, obesidad, radiología y laboratorio clínico.
Actualizada, rigurosa y aplicada a la realidad regional, esta obra entrega herramientas clave para el razonamiento clínico, la interpretación de exámenes y la toma de decisiones terapéuticas basadas en evidencia, consolidándose como un texto de referencia para estudiantes, residentes y especialistas.
Prebiotic Potential of Brewer’s Spent Grain Residual Solid After Enzymatic Hydrolysis: Evidence from a Colonic Fermentation Study
(MDPI, 0026-07-03) Vargas-Straube, María José; Rojas-Hidalgo, Francisca; Nunes de Oliveira, Jordana; Arancibia, Boris; Mariano de Albuquerque, Thatyane; Alenkar Bezerra, Taliana; Torres de Souza, Eike; Leite de Souza, Evandro; Mariotti-Celis, María Salomé; Zúñiga, María Elvira; Fuentes, Lida; Soto-Maldonado, Carmen
Brewer’s spent grain (BSG), the main by-product of the brewing industry, is a rich source of arabinoxylans (AXs) and hydroxycinnamic acids, particularly ferulic acid (FA), which contribute to its prebiotic potential. This study evaluates the prebiotic properties of residual solid from an enzymatically treated BSG, compared to the properties of BSG as a non-enzymatically hydrolyzed control. Although the residual solid exhibited total polyphenol (2581.96 ± 70.63 mg/100 g dry weight) and FA (180.84 ± 3.28 mg/100 g dry weight) contents comparable to those of the non-hydrolyzed control (2500.38 ± 284.20 and 179.59 ± 3.30 mg/100 g dry weight, respectively), the AX content was significantly higher (14,084.81 ± 185.72 mg/100 g), accompanied by a lower degree of feruloylation (12.84 ± 0.23 mg FA/g AX), higher antioxidant activity (64,825.35 ± 4011.24 μmol TE/100 g), and structural changes visualized by scanning electron microscopy. In addition, in vitro colonic fermentation showed a delayed butyrogenic profile, with increased butyrate production compared to the control (3.17 ± 1.44 mM). Microbiota analysis by fluorescence in situ hybridization (FISH) coupled with flow cytometry indicated an increase in butyrate-producing bacteria, including Faecalibacterium prausnitzii (+5.90) and Eubacterium rectale (+6.88). Growth of Bacteroides, Lactobacillus, and Bifidobacterium spp. was also promoted. Overall, these findings suggest that enzymatic processing of BSG can generate a residual solid with modified structural characteristics and potential prebiotic functionality, supporting its potential application as a fermentable flour ingredient in functional foods.
Real-Time Ultrasonic Inspection System for Oil Content in Emulsions for Production Lines
(IEEE, 2025-10-28) Galleguillos Silva, Renato Bruno; Paloma, Ponce
This work presents a real-time ultrasonic inspection system with temperature compensation for monitoring oil content in emulsion production lines across food, pharmaceutical, cosmetic and oil refining industries. The system enables continuous, non-destructive quality control by measuring ultrasonic wave propagation velocity through oil-in-water (O/W) emulsions. A specialized measurement chamber with submersible piezoelectric transducers and automated signal processing algorithms provides accurate concentration estimates within 2% error of actual values. Experimental validation with almond oil emulsions demonstrates a strong linear correlation between propagation velocity and oil concentration, with temperature compensation ensuring reliability under industrial operating conditions. The system’s non-invasive nature and real-time capabilities make it
suitable for inline implementation in production lines, offering significant advantages over traditional batch testing methods. Index Terms—inline inspection, ultrasonic monitoring, emulsion production, food processing, pharmaceutical manufacturing, cosmetic production, water recovery
Green ultrasound-sssisted extraction of bee Pollen polyphenols for bioactive κ-carrageenan food packaging films with antioxidant and UV-protective properties
(American Chemical Society, 2026-06-23) Galdames, Franco; Galleguillos Silva, Renato Bruno; Cabreras-Barjas, Gustavo; Faúndez, Mario; Giordano, Ady; Castaño, Patricia; Marambio, Esteban; Montenegro, Gloria; Velásquez, Patricia
Bee pollen extracts can enhance the properties of biopolymeric films. This study is the first to extract polyphenols from bee pollen using ultrasound-assisted glycerol–water mixtures for incorporation into κ–carrageenan–based films. First, bee pollen polyphenols were extracted and optimized using Box–Behnken response surface methodology, considering glycerol concentration, sonication amplitude, and extraction time. Then, the optimized extracts were characterized. Finally, the effects of incorporating the extracts into κ–carrageenan films were assessed through physicochemical and mechanical analyses. The optimized bee pollen extracts showed total phenolic contents ranging from 609.4 to 1431.3 μg GAE/g. Higher sonication amplitude, increased glycerol concentration, and shorter extraction time increased polyphenolic extraction. The extracts also exhibited high antioxidant capacity and low cytotoxicity. The incorporation of bee pollen extracts modified several functional properties of the κ–carrageenan films. Films with these extracts showed increased antioxidant capacity, rigidity and UV protection, reduced thickness and solubility. The results indicate that films with bee pollen extract appear better suited as rigid protective coatings or wrapping films for low–stress applications rather than as flexible, stretchable packaging.