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Sistema de Bibliotecas Universidad Finis Terrae
El Repositorio Institucional de la Universidad FinisTerrae, es gestionado por el Sistema de Bibliotecas y tiene por objetivo permitir el acceso libre a la producción académica e institucional de la Universidad, aumentando la visibilidad de sus contenidos y garantizando su conservación.
Envíos recientes
Comprehensive Structural, Electronic, and Biological Characterization of fac-[Re(CO)3(5,6-epoxy-5,6-dihydro-1,10-phenanthroline)Br]: X-Ray, Aromaticity, Electrochemistry, and HeLa Cell Viability
(MPDI, 2025-12-21) Carreño, Alexander; Artigas, Vania; Ancede-Gallardo, Evys; Morales-Guevara, Rosaly; Leyva-Parra, Luis; Luis Leyva-Parra; Martí, Angel A.; Videla, Camila; Otero, María Carolina; Gacitúa, Manuel
The rhenium(I) tricarbonyl complex fac-[Re(CO)3(5,6-epoxy-5,6-dihydro-1,10-phenanthroline)Br] (ReL) has previously demonstrated promising luminescent properties, enabling its direct application as a probe for walled cells such as Candida albicans and Salmonella enterica. In this new study, we present a significantly expanded and comprehensive characterization of ReL, incorporating a wide range of experimental and computational techniques not previously reported. These include variable-temperature 1H and 13C NMR spectroscopy, CH-COSY, single-crystal X-ray diffraction, Hirshfeld surface analysis, DFT calculations, Fukui functions, non-covalent interaction (NCI) indices, and electrochemical profiling. Structural analysis confirmed a pseudo-octahedral geometry with the bromide ligand positioned cis to the epoxy group. NMR data revealed the coexistence of cis and trans isomers in solution, with the trans form being slightly more stable. DFT calculations and aromaticity descriptors indicated minimal electronic differences between isomers, supporting their unified treatment in subsequent analyses. Electrochemical studies revealed two oxidation and two reduction events, consistent with ECE and EEC mechanisms, including a Re(I) → Re(0) transition at −1.50 V vs. SCE. Theoretical redox potentials showed strong agreement with experimental data. Biological assays revealed a dose-dependent cytotoxic effect on HeLa cells, contrasting with previously reported low toxicity in microbial systems. These findings, combined with ReL’s luminescent and antimicrobial properties, underscore its multifunctional nature and highlight its potential as a bioactive and imaging agent for advanced therapeutic and microbiological applications.
Uncovering the muscle clock–mitochondria axis through exercise
(CellPress, 2025-12) Castro-Sepulveda, Mauricio
Emerging evidence suggests an interplay between the molecular clock and mitochondrial dynamics in skeletal muscle. In this Forum article, we hypothesize that exercise, as a metabolic challenge, provides a powerful physiological model to investigate the clock–mitochondria axis and its regulatory role in muscle function and metabolic health in humans.
Press and School Violence: Subjective Theories in the Post-Pandemic Narratives in Chilean Online Newspaper
(MDPI, 2025-12-18) Rodríguez-Pastene, Fabiana; Sorza Sara; Castro-Carrasco, Pablo J.; Carrasco-Aguilar, Claudia; Gubbins, Verónica; Caamaño-Vega, Vladimir; Zelaya, Martina
This study examines how the explanations about school violence are constructed in Chilean online newspapers after the country—which had the longest period of school closures— returned to in-person classes. During early 2022, several complaints of school violence surged compared to the lockdown years, prompting questions about how the media shaped public interpretations of this rise. Using a content analysis of three Chilean online newspapers (“SoyChile”, “ElMostrador”, and “LUN”), this study reconstructed the Subjective Theories (STs) conveyed in their coverage. All articles (n = 50) published during three strategic periods of the 2022 school year were analyzed to identify explicit and implicit theories about the causes, intervening conditions, and strategies for addressing school violence. The most prevalent ST framed school violence as a structural problem, appearing 27 times. This narrative portrays the phenomenon as both inevitable and beyond the control of key actors, such as caregivers, teachers, school leaders, authorities, and students, ultimately reducing perceived accountability and agency in prevention or intervention efforts. Media discourse tended to legitimize explanations that locate school violence outside the sphere of individual or institutional responsibility
Intervención en una sala de estimulación multisensorial Snoezelen en el Centro de Desarrollo Infantil Ruku, de la comuna de Las Condes, Región Metropolitana de Chile: competencias profesionales y aportes desde las neurociencias a la formación personal por vía corporal
(Universidad de Morón, 2025) Haddad, Karin; Donoso, Claudia; Quijada Claudia; Sanhueza Javier
La implementación de salas multisensoriales Snoezelen ha demostrado ser una herramienta valiosa en contextos terapéuticos y de desarrollo infantil, al ofrecer entornos controlados que favorecen la estimulación sensorial y los procesos adaptativos. En este marco, el presente estudio explora las competencias profesionales necesarias y desplegadas en la intervención de dos profesionales (Terapeutas Ocupacionales) dentro de una sala multisensorial Snoezelen, Implementada en el Centro de Desarrollo Infantil RUKU, ubicado en la comuna de Las Condes Región Metropolitana de Chile y los posibles aportes desde las neurociencias a la formación personal por vía corporal de las Terapeutas Ocupacionales.
A través de un enfoque cualitativo, se analizan las prácticas de ambas profesionales y cómo el conocimiento neurocientífico enriquece sus intervenciones. Sin embargo, se observa una limitación en su formación desde la disciplina de la psicomotricidad y específicamente en la formación personal por la vía corporal, lo cual permite trabajar desde el “ser” y no solo desde el “hacer”. Los resultados destacan que, aunque las profesionales poseen una base sólida en Neurociencias, la falta de esta formación integral reduce el potencial de la intervención, limitando la creación de vínculos relacionales profundos y empáticos
The implementation of multisensory Snoezelenrooms has proven to be a valuable tool in therapeutic and child development contexts, offering controlled environments for sensory stimulation and the facilitation of adaptive processes. Within this framework, the present study explores the professional competencies necessary for and deployed in the intervention of two professionals (Occupational Therapists) within a Snoezelen multisensory room, implemented at the RUKU Child Development Center, located in the commune of Las Condes, Metropolitan Region of Chile. It also analyzes the potential contributions from neurosciences to the personal training through bodily experience of Occupational Therapists. Using a
qualitative approach, the practices of both professionals are analyzed, and how neuroscientific knowledge enriches their interventions. However, a limitation is observed in their training from the discipline of psychomotricity and specifically in personal training through bodily experience, which allows working from "being" and not just from "doing." The results highlight that, although the professionals possess a solid foundation in neurosciences, the lack of this comprehensive training reduces the potential of the intervention, limiting the creation of deep and empathetic relational bonds.
Inteligencia emocional y liderazgo de estudiantes universitarios: un estudio comparado en Chile, México y España
(Octaedro Editorial, 2025) Lomboy Finsterbusch, Maven; López González, Jorge
Esta investigación evaluó la relación entre la inteligencia emocional (IE) y elliderazgo de estudiantes de las universidades Finis Terrae (Chile), Francisco de Vitoria (España) y Anáhuac (México). Se realizaron dos análisis: uno sobre la relación entre IE y liderazgo auténtico, y otro entre IE y liderazgo virtuoso, utilizando un enfoque cuantitativo. Se aplicaron el cuestionario WLEIS de Wong y Law (2002) para medir IE, el ALQ de Walumbwa et al. (2008) para liderazgo auténtico y una versión del cuestionario LID (López González et al., 2023) para liderazgo virtuoso.
Los resultados revelaron una correlación positiva entre IE y liderazgo. Los estudiantes encuestados mostraron mayores habilidades en la interacción externa, y menores en la exploración interna. Además, se observó que la IE y el liderazgo no están determinados por el sexo ni el área disciplinar, pues varían según el país. Estos hallazgos son significativos para la educación en liderazgo de universitarios.