Medicina
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Ultrasound evaluation of a new surface reference line to describe sural nerve location and safe zones to consider in posterior leg approaches
(Springer, 2022-12-26)Purpose Several authors have described methods to predict the sural nerve pathway with non-proportional numerical distances, but none have proposed a person-proportional, reproducible method with anatomical references. The ... -
Latin American Consensus on the Management of Sepsis in Children: Sociedad Latinoamericana de Cuidados Intensivos Pediátricos [Latin American Pediatric Intensive Care Society] (SLACIP) Task Force: Executive Summary
(SAGE Publications, 2022)Objective: The aim of this study was to develop evidence-based recommendations for the diagnosis and treatment of sepsis in children in low- and middle-income countries (LMICs), more specifically in Latin America. Design: ... -
Infancia y COVID-19: Los efectos indirectos de la pandemia COVID-19 en el bienestar de niños, niñas y adolescentes
(Sociedad Chilena de Pediatría, 2022)El impacto de la pandemia COVID-19 ha sido invisibilizado en niños, niñas y adolescentes, ya que muchos de los efectos negativos han sido producto de las medidas de contención y mitigación, y sólo serán cuantificables a ... -
Clinical and organizational framework of repurposing pediatric intensive care unit to adult critical care in a resource-limited setting: Lessons from the response of an urban general hospital to the COVID-19 pandemic
(Elsevier, 2022)Purpose We aim to describe the action plan and clinical results of a COVID-19 unit for adult patient care in units intended for critically ill children, proposing a clinical/administrative framework. Methods We reviewed ... -
Mechanical power in pediatric acute respiratory distress syndrome: A PARDIE study
(BMC, 2022-01)Background: Mechanical power is a composite variable for energy transmitted to the respiratory system over time that may better capture risk for ventilator-induced lung injury than individual ventilator management components. ... -
Scientific publication speed and retractions of COVID-19 pandemic original articles.
(World Health Organization, 2022)Objective. To describe the editorial processing time of published COVID-19 research articles and com-pare this with a similar topic, human influenza, and analyze the number of publications, ... -
Mielitis flácida aguda e infeccion por enterovirus: una enfermedad grave emergente.
(Sociedad Chilena de Pediatría, 2022)La mielitis flácida aguda (MFA) es una enfermedad neuroinflamatoria de la medula espinal caracterizada por la aparición aguda de parálisis flácida asimétrica de predominio proximal y una lesión longitudinal de la sustancia ... -
¿Por qué estudiar sobrecarga de fluidos en niños graves? Revocación médica, heterogeneidad y resistencia al cambio.
(Sociedad Chilena de Pediatría, 2022) -
Spontaneous Breathing Promotes Lung Injury in an Experimental Model of Alveolar Collapse
(Nature Research, 2022)Vigorous spontaneous breathing has emerged as a promotor of lung damage in acute lung injury, an entity known as “patient self-inflicted lung injury”. Mechanical ventilation may prevent this second injury by decreasing ... -
Increasing Immune Dysfunction is Associated with Increasing Matrix-Metalloproteinase-2 Expression and Predicts Biochemical Failure in Men with Bone Marrow Micro-Metastasis Positive Localized Prostate Cancer
(Asian Pacific Organization for Cancer Prevention (APOCP), 2022-07)Abstract Introduction: To determine if there was an association of the ALC (absolute lymphocyte count) and LCP (lymphocytopenia) with the expression of MMP-2 in bone marrow micro-metastasis, the changes occurring ... -
The CAPRA-S Score and Immune Dysfunction as a Guide to Outcome in Men Treated with Prostatectomy Radical as Mono-Therapy for Prostate Cancer
(2022-08)Objective: Incorporate the immune function as determined by the absolute lymphocyte count (ALC) into the CAPRA-S risk stratification score to determine if predictive values could be improved. Materials and Methods: The ... -
Regulation of the intestinal extra-adrenal steroidogenic pathway component LRH-1 by glucocorticoids in ulcerative colitis
(MDPI, 2022-06-12)Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) and can be treated with glucocorticoids (GC), although some patients are unresponsive to this therapy. The transcription factor LRH-1/NR5A2 is critical to ... -
Dysregulated Immune Responses in COVID-19 Patients Correlating With Disease Severity and Invasive Oxygen Requirements.
(Frontiers Media, 2021-10-21)The prognosis of severe COVID-19 patients has motivated research communities to uncover mechanisms of SARS-CoV-2 pathogenesis also on a regional level. In this work, we aimed to understand the immunological dynamics of ... -
Asociación del nivel socioeconómico y educacional en los egresos por cáncer de mama en Chile durante los años 2001 al 2016
(Revista ANACEM, 2021)Introducción El cáncer de mama constituye la primera causa de muerte en los cánceres en Chile según Globocan 2018. Dentro de los factores que explican esta alta mortalidad encontramos una baja tasa de detección y de ... -
Atypical presentation of COVID-19: Chronic bilateral testicular pain with lower extremity peripheral polyneuropathy, case report
(Elsevier, 2022-01)In context of COVID-19 pandemic, there has been different presentations of the infection. The relationship of testicular pain with COVID-19 has not been extensively studied. We present a 31 years old male, with SARS-COV-2 ... -
Improvement in the neutrophil-lymphocyte ratio after combined FOLFOX chemotherapy for stage III colon cancer is associated with improved minimal resdiual disease and outcome
(Asian pacific journal of cancer prevention, 2022-02-19)Introduction: Minimal residual disease (MRD) is the net result of the biological properties of disseminated tumour cells and the effect of the immune system and treatment to eliminate them. The aim of this study was to ... -
En época de COVID-19: ¿cómo las estrategias de recuperación avanzadas (STAR) pueden ayudar a dar soluciones a los pacientes oncológicos?
(Revista Chilena de Medicina, 2021-01-11)Background: SARS-CoV-2 hampered the resolution of multiple diseases, including cancer. Aim: To show that a multidisciplinary program of Strategies to Advance Recovery (STAR) can be implemented in a public hospital in ... -
Spanish translation, face validity, and reliability of the ICIQ-B Questionnaire with colorectal cancer patients
(Thieme Gruppe, 2021-06)Purpose To describe the English-to-Spanish translation process and preliminary psychometric analysis (face validity, cultural adaptation, and test-retest reliability) of the International Consultation on Incontinence ... -
A randomized clinical trial to assess the effectiveness of pre- and post-surgical pelvic floor physiotherapy for bowel symptoms, pelvic floor function, and quality of life of patients with rectal cancer: CARRET protocol
(BMC, 2021-01)Background: There is scarcity of trials about preventative strategies for low anterior resection syndrome (LARS) in rectal cancer patients. The aim of this study is to evaluate the effectiveness of a pre- and post-surgical ... -
Therapeutic plasma exchange in critically ill children: experience of the pediatric intensive care unit of two centers in Chile
(Elsevier, 2021-06-04)Introduction : Therapeutic plasma exchange (TPE) is an extracorporeal blood purification technique used in a wide spectrum of diseases. We aim to review the indications, complications, and outcomes of critically ill children ...
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