Artículos de Revistas

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https://repositorio.uft.cl/handle/20.500.12254/2477

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Examinando Artículos de Revistas por Materia "Caries"

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    Ítem
    Antimicrobial effect of copper nanoparticles on relevant supragingival oral bacteria
    (MDPI, 2024-03-20) Oetiker, Nia; Salinas, Daniela; Lucero-Mora, Joaquín; Orellana, Rocío; Quiroz-Muñoz, Mariana; Bravo, Denisse; Pérez-Donoso, José M.
    Copper nanoparticles (Cu NPs) show promise in dentistry for combating bacterial dysbiosis and tooth decay. Understanding their effects on commensal versus pathogenic bacteria is vital for maintaining oral health balance. While Cu NPs demonstrate antibacterial properties against various oral bacteria, including common pathogens associated with tooth decay, their impact on commensal bacteria requires careful examination. In our work, we analyzed three types of Cu NPs for their effects on the growth, viability, and biofilm formation of representative caries-associated and commensal oral bacteria. S. sanguinis showed high tolerance to all Cu NPs, while L. rhamnosus was highly sensitive. Oxide-Cu NPs exhibited a stronger inhibitory effect on pathobionts compared with commensal bacteria. Moreover, the biofilm formation of the key cariogenic bacteria S. mutans was reduced, with minimal negative effects on commensal species’ biofilm formation. All our results showed that CuO nanoparticles (CuO NPs) exhibit reduced toxicity toward commensal bacteria growth and development but have a strong impact on pathogens. This suggests their potential for targeted treatments against pathogenic bacteria, which could help in maintaining the balance of the oral bacterial community.
  • Miniatura
    Ítem
    Structural determinants explain caries differences among preschool children in Chile’s Metropolitan Region
    (BioMed Central, 2023-03-09) Monsalves, María José; Espinoza, Iris; Moya, Patricia; Aubert, Josefina; Duran, Doris; Arteaga, Oscar; Kaufman, Jay S; Bangdiwala, Shrikant
    Objective To estimate the association between Social Determinants of Health (structural and intermediate) and caries indicators in Chile’s Metropolitan Region preschool children. Methods A multilevel cross-sectional study of Social Determinants of Health (SDH) and caries in hildren aged 1 to 6 years in Chile’s Metropolitan Region was conducted in 2014–2015, with three levels: district, school and child. Caries were assessed by the dmft-index and the prevalence of untreated caries. The structural eterminants analyzed were Community Human Development Index (CHDI), urban/rural location, school type, caregiver’s education and family income. Poisson multilevel regression models were fit. Results The sample size was 2,275 children from 40 schools in 13 districts. While the highest CHDI district had an untreated caries prevalence of 17.1% (12.3–22.7%), in the most disadvantaged district it was 53.9% (95% CI 46.0–61.6%). As family income increased, the probability of untreated caries prevalence decreased (PR = 0.9 95% CI 0.8–1.0). Rural districts had an average dmft-index of 7.3 (95% CI 7.2–7.4), while in urban districts, it was 4.4 (95% CI 4.3–4.5). Higher probabilities of untreated caries prevalence (PR = 3.0 95% CI 2.3–3.9) were observed in rural children. Greater probabilities of untreated caries prevalence (PR = 1.3 95% CI 1.1–1.6) and prevalence of caries experience (PR = 1.3 95% CI 1.1–1.5) were observed in children whose caregivers had a secondary educational level. Conclusions A strong association was observed between the social determinants of health, specifically the structural ones, and the caries indicators studied in children of the Metropolitan Region of Chile. There were notable differences in caries between districts according to social advantage. Rurality and caregiver’s education were the most consistent predictors.