Prevalence of non-alcoholic fatty liver disease and its association with lifestyle habits in adults in Chile: a cross-sectional study from the National Health Survey 2016-2017

dc.contributor.authorFernández-Verdejo, Rodrigo
dc.date.accessioned2023-01-11T14:51:42Z
dc.date.available2023-01-11T14:51:42Z
dc.date.issued2023-01
dc.description.abstractNon-alcoholic fatty liver disease (NAFLD) represents an excessive fat accumulation within the liver, usually associated with excess body weight. A liver biopsy is the gold standard for diagnosis, but it is inapplicable in population-based studies. In large populations, non-invasive methods could be used, which may also serve to identify potential protective factors. We aimed to: [a] estimate NAFLD prevalence in the adult population in Chile by using non-invasive methods; and [b] determine the association between the presence of NAFLD and lifestyle habits. The National Health Survey of Chile 2016-2017 was analysed. We included individuals aged 21-75 years, without infectious diseases nor risky alcohol consumption. NAFLD was detected by either Fatty Liver Index (FLI; considers circulating triglycerides, circulating gamma-glutamyl-transferase, body mass index, and waist circumference), Lipid Accumulation Product (LAP; considers sex, circulating triglycerides, and waist circumference), or their combination. Lifestyle habits were determined by questionnaires. We included 2,774 participants, representative of 10,599,094 [9,831,644-11,366,544] adults in Chile. NAFLD prevalence [95%CI] was 39.4% [36.2-42.8] by FLI, 27.2% [24.2-30.4] by LAP, and 23.5% [20.7-26.5] by their combination. The prevalence progressively increased with increasing body mass index. Less smoking, and more moderate-vigorous physical activity and whole-grain consumption were associated with lower odds of having NAFLD, independently of body mass index. At least one out of four adults in Chile is afflicted with NAFLD. Health promotion strategies focused on controlling excess body weight and promoting specific lifestyle habits are urgently required.en
dc.identifier.citationBritish Journal of Nutrition, Vol. 130, N°6 (2023), p. 1036-1046.
dc.identifier.doihttps://doi.org/10.1017/S0007114523000028
dc.identifier.issn0007-1145
dc.identifier.issne1475-2662
dc.identifier.orcidhttps://orcid.org/0000-0002-5948-2281es
dc.identifier.urihttp://hdl.handle.net/20.500.12254/2641
dc.language.isoenes
dc.publisherCambridge University Pressen
dc.subject.otherDieten
dc.subject.otherExercise
dc.subject.otherObesityen
dc.subject.otherSmokingen
dc.titlePrevalence of non-alcoholic fatty liver disease and its association with lifestyle habits in adults in Chile: a cross-sectional study from the National Health Survey 2016-2017en
Archivos
Bloque original
Mostrando 1 - 1 de 1
Cargando...
Miniatura
Nombre:
Pettinelli et al. 2023.pdf
Tamaño:
184.38 KB
Formato:
Adobe Portable Document Format
Descripción:
Texto referencial
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
638 B
Formato:
Item-specific license agreed upon to submission
Descripción: