Puesta al día: carcinoma paratiroideo

dc.contributor.authorSilva-Figueroa, Angélicaes
dc.contributor.authorBarberán, Marcelaes
dc.contributor.authorCampusano, Claudiaes
dc.contributor.authorSalman, Patricioes
dc.contributor.authorTrejo, Pamelaes
dc.contributor.authorRivera, Sandraes
dc.contributor.authorFlorenzano, Pabloes
dc.contributor.authorVelasco, Soledades
dc.contributor.authorIllanes, Franciscaes
dc.contributor.authorTrincado, Patricioes
dc.contributor.authorCanessa, Josées
dc.contributor.authorSolar, Antonietaes
dc.contributor.authorMarcela, Morenoes
dc.contributor.authorEugenin, Danielaes
dc.contributor.authorJiménez, Beatrizes
dc.contributor.authorArroyo, Patriciaes
dc.date.accessioned2021-12-15T18:50:04Z
dc.date.available2021-12-15T18:50:04Z
dc.date.issued2021
dc.description.abstractParathyroid carcinoma is a rare malignant disease that presents as a sporadic or familial primary hyperparathyroidism (PHP). The latter is associated with some genetic syndromes. It occurs with equal frequency in both sexes, unlike PHP caused by parathyroid adenoma that is more common in women. It hould be suspected in cases of severe hypercalcemia, with high parathyroid hormone levels and a palpable cervical mass. Given the difficulty in distinguishing between parathyroid carcinoma and adenoma prior to the surgery, the diagnosis is often made after parathyroidectomy. The only curative treatment is complete surgical resection with oncologic block resection of the primary tumor to ensure free margins. Adjuvant therapies with chemotherapy or radiation therapy do not modify overall or disease-free survival. Recurrences are common and re-operation of resectable recurrent disease is recommended. The palliative treatment of symptomatic hypercalcemia is crucial in persistent or recurrent disease after surgery since morbidity and mortality are more associated with hypercalcemia than with tumor burden.en_US
dc.identifier.citationRevista Médica de Chile, Vol. 149, N° 3 (2021) p. 399-408.es
dc.identifier.doihttp://dx.doi.org/10.4067/s0034-98872021000300399
dc.identifier.issn0034-9887
dc.identifier.orcidhttps://orcid.org/0000-0002-4992-7072
dc.identifier.urihttp://hdl.handle.net/20.500.12254/2132
dc.language.isoeses
dc.publisherSociedad Médica de Santiago; Sociedad Chilena de Medicina Interna es
dc.rightsAtribución-NoComercial-CompartirIgual 3.0 Chile (CC BY-NC-SA 3.0 CL)
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/cl/
dc.subject.otherDiagnosises
dc.subject.otherHypercalcemiaes
dc.subject.otherHyperparathyroidismen_US
dc.subject.otherParathyroid neoplasmsen_US
dc.titlePuesta al día: carcinoma paratiroideoes
dc.title.alternativeAn update on parathyroid carcinomaen_US
dc.typeArtículoes
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