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Immune dysfunction, minimal residual disease and patient outcome in non-metastatic cancer; could modulation of immune function improve outcome
| dc.contributor.author | Murray, Nigel P | |
| dc.date.accessioned | 2021-12-17T12:01:15Z | |
| dc.date.available | 2021-12-17T12:01:15Z | |
| dc.date.issued | 2021-02 | |
| dc.description.abstract | Immune modulation by the primary tumour, by surgical resection and adjuvant treatment combined with the biological characteristics of the tumour cell subpopulations will determine patient outcome. In patients with mRD, combined low dose metronomic chemotherapy may improve immune function and the effect of combination therapy to eliminate MRD or may be sufficient to maintain disseminated tumour cells in a dormant state prolonging disease free survival with minimal side effects. the ability to measure and phenotype subtypes of MRD provides an early detection of disease response or progression and determining the most adequate therapy. In asymptomatic patients lower toxicity compared with conventional chemotherapy is important | es |
| dc.identifier.citation | Future Oncol 2021; 17: 1571-1575 http://doi.org:10.2217/fon-2020-1259 | es |
| dc.identifier.issn | 1479-6694 | |
| dc.identifier.orcid | 0000-0001-8154-8550 | es |
| dc.identifier.orcid | 10.2217/fon-2020-1259 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12254/2139 | |
| dc.language.iso | en | es |
| dc.publisher | Future Science Group | es |
| dc.relation.ispartofseries | Future Oncology; | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/cl/ | |
| dc.rights.uri | ||
| dc.subject.other | Circulating tumour cells | es |
| dc.subject.other | Immune dysfunction | es |
| dc.subject.other | Micrometastasis | es |
| dc.subject.other | Minimal residual disease | es |
| dc.subject.other | Non metastatic cancer | es |
| dc.subject.other | Prognosis | es |
| dc.title | Immune dysfunction, minimal residual disease and patient outcome in non-metastatic cancer; could modulation of immune function improve outcome | es |
| dc.type | Artículo | es |
| dcterms.accessRights | El artículo completo no puede ser publicado en el Repositorio Institucional debido a los permisos de copyright definidos por la editorial publicadora |
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