Internal carotid artery agenesis: a systematic review of prevalence, basal brain circulation variations, and associated pathologies

Vista sencilla de ítem
dc.contributor.authorOrellana-Donoso, Mathias
dc.contributor.authorSanchis-Gimeno, Juan
dc.contributor.authorAfandi-Rebolledo, Sary
dc.contributor.authorNova-Baeza, Pablo
dc.contributor.authorGarcía-Mena, Paloma
dc.contributor.authorSuazo Santibañez, Alejandro
dc.contributor.authorPeñailillo-Ibarra, Rocío
dc.contributor.authorValdés-Orrego, Iván
dc.contributor.authorValenzuela Fuenzalida, Juan José
dc.date.accessioned2025-09-30T13:12:39Z
dc.date.available2025-09-30T13:12:39Z
dc.date.issued2025-07-05
dc.description.abstractThe internal carotid artery (ICA) is a crucial vessel, and its congenital absence, known as ICA agenesis, is a rare vascular anomaly. This systematic review aimed to provide a comprehensive overview of the available evidence on this condition. We systematically searched multiple databases from inception until January 2024. Two authors independently screened titles and abstracts, and a third reviewer was involved if consensus could not be reached. Data extraction and quality assessment were performed using validated the AQUA tool and the JBI critical appraisal checklist tool. A total of 138 (7.8%) articles out of 1,778 met the inclusion criteria, reporting 2040 subjects from which 176 presented (8.6%) ICA agenesis. Most of the studies were case reports (96%), and the included studies originated from various countries, with the United States (17.39%), Japan (14.49%), Turkey (10.87%), and India (10.14%) contributing the most. Left-sided agenesis was the most common (67.39%), followed by right-sided (42.03%) and bilateral (22.46%) agenesis. The most reported clinical manifestations were Horner’s syndrome, increased risk of intracranial aneurysms, and pituitary gland abnormalities. ICA agenesis is a rare vascular anomaly with a left-sided predominance. While some patients may develop associated clinical conditions, many remain asymptomatic due to the development of robust collateral circulation. Comprehensive preoperative evaluation and awareness of these anatomical variations are crucial to guide surgical planning and minimize the risk of complications. PROSPERO registration number: CRD42024592673.
dc.identifier.citationAnatomical Science International, (2025) p. 1-37.
dc.identifier.doihttps://doi.org/10.1007/s12565-025-00873-y
dc.identifier.issn1447-6959
dc.identifier.issne1447-073X
dc.identifier.orcidhttps://orcid.org/0000-0002-1781-062X
dc.identifier.urihttps://hdl.handle.net/20.500.12254/4326
dc.language.isoen
dc.publisherSpringer Nature
dc.rightsAtribución-NoComercial-CompartirIgual 3.0 Chile (CC BY-NC-SA 3.0 CL)
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/cl/
dc.subjectInternal carotid artery
dc.subjectAgenesis
dc.subjectAplasia
dc.subjectPrevalence
dc.subjectClinical associations
dc.subjectSurgical implications
dc.subjectCollateral circulation
dc.subjectAnatomical variations
dc.subjectEmbryonic development
dc.titleInternal carotid artery agenesis: a systematic review of prevalence, basal brain circulation variations, and associated pathologies
dc.typeArticle
dcterms.accessRightsEl artículo completo no puede ser publicado en el Repositorio Institucional debido a los permisos de copyright definidos por la editorial publicadora. Ingrese a través del DOI.
Archivos
Bloque original
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
Paper10-Internalcarotidartery.pdf
Tamaño:
1.9 MB
Formato:
Adobe Portable Document Format
Descripción:
Texto referencial
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
347 B
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
Colecciones
Artículos de Revistas