Hypoplastic and congenital absence of coronary arteries and Its correlation with clinical implications of cardiac circulation: a systematic review and meta-analysis

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dc.contributor.authorBruna Mejias, Alejandro
dc.contributor.authorDel Villar Valdebenito, Javiera
dc.contributor.authorRomán, Camila
dc.contributor.authorAlcaíno Adasme, Catalina
dc.contributor.authorSepulveda Loyola, Walter
dc.contributor.authorOrellana-Donoso, Mathias
dc.contributor.authorNova Baeza, Pablo
dc.contributor.authorSuazo Santibañez, Alejandra
dc.contributor.authorBecerra Farfan, Alvaro
dc.contributor.authorSanchis Gimeno, Juan
dc.contributor.authorValenzuela Fuenzalida, Juan José
dc.date.accessioned2025-03-10T15:56:16Z
dc.date.available2025-03-10T15:56:16Z
dc.date.issued2024-04-18
dc.description.abstractBackground: Coronary arteries originate from the first portion of the aorta, emerging from the right and left aortic sinuses. They traverse through the subepicardium and coronary sulcus to supply the myocardium during diastolic function. The objective of this review was to understand how the hypoplasia and agenesis of the coronary arteries are associated with cardiac pathologies. Methods: The databases Medline, Scopus, Web of Science, Google Scholar, CINAHL, and LILACS were researched until January 2024. An assurance tool for anatomical studies (AQUA) was used to evaluate methodological quality. The pooled prevalence was estimated using a random effects model. Results: A total of three studies met the established selection criteria for inclusion in this meta-analysis. The prevalence of coronary artery variants was 3% (CI = 2% to 8%), with a heterogeneity of 77%. The other studies were analyzed descriptively, along with their respective clinical considerations in the presence of the variant. Conclusions: Hypoplasia and the congenital absence of the coronary arteries are often incidental findings and understanding these variants is crucial to prevent misdiagnosis. Additionally, it is essential to exercise caution when considering surgical management for hearts with these variants.
dc.identifier.citationJournal of Clinical Medicine, Vol 13, N°11, 3085 (2024) p. 1-23.
dc.identifier.doihttps://doi.org/10.3390/jcm13113085
dc.identifier.issne2077-0383
dc.identifier.orcidhttps://orcid.org/0000-0002-1781-062X
dc.identifier.urihttp://hdl.handle.net/20.500.12254/4052
dc.language.isoen
dc.publisherMDPI
dc.rightsAtribución-NoComercial-CompartirIgual 3.0 Chile (CC BY-NC-SA 3.0 CL)
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/cl/
dc.subjectAnatomy coronary artery
dc.subjectHypoplastic coronary artery
dc.subjectAgenesia coronary artery
dc.subjectClinical anatomy
dc.subjectVariations anatomical
dc.titleHypoplastic and congenital absence of coronary arteries and Its correlation with clinical implications of cardiac circulation: a systematic review and meta-analysis
dc.typeArticle
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