Cocaine polydrug use and its impact on intentional harm recognition: a highdensity EEG study

Archivos
s40359-025-03145-6.pdf (1.83 MB)
Fecha
2025-08-14
Nota de Acceso
Fecha de embargo
Autores
Profe guía
Perfil ORCID
https://orcid.org/0000-0002-7304-5256
Título de la revista
ISSN de la revista
Título del volumen
Editor
Springer Nature
ISBN
ISSN
ISSNe
2050-7283
DOI
https://doi.org/10.1186/s40359-025-03145-6
URI
https://hdl.handle.net/20.500.12254/4346
Resumen
Background Cocaine and stimulant consumption constitute a significant global issue and are associated with impaired social skills. However, the relationship between substance abuse and intentional harm recognition remains unclear. Intentional harm recognition is a crucial social cognitive ability that allows individuals to determine whether a harmful action performed by another person is deliberate or accidental. Methods The present study examined self-reported, behavioural, and neural responses associated with intentional harm recognition in n = 19 cocaine polydrug users (COC) and n = 19 healthy controls (HC). High-density electroencephalography (hdEEG) was used to measure brain activity during an Intentional Inference Task (IIT), which assesses fast intention recognition in scenarios involving deliberate or unintentional harm to people and objects. This study took place between 2014 and 2015 in Santiago, Chile. Results Behaviorally, COC exhibited slower reaction times (RT) than HC. Event-related potential (ERP) analysis revealed late frontal differences in HC when attributing intentional harm, while these differences were absent in COC. Conclusions These findings suggest a potential shift in COC towards emotional over-involvement and away from rational cognitive assessment of social information. The present results provide new insights into the recognition of intentional harm processing in cocaine polydrug users and highlight the potential clinical benefits of interventions focused on socio-emotional regulation training.
Descripción
Lugar de Publicación
Sponsorship
Este trabajo fue apoyado por subvenciones de la Comisión Nacional de Investigación Científica y Tecnológica (ANID/FONDECYT Regular N°1231117 a David Huepe.
Citación
BMC Psychology, Vol. 13, N° 917 (2025) p. 1-12.
Palabras clave
Substance use disorder, Social cognition, Intentional harm recognition, Intentional inference task (IIT)
Licencia
Atribución-NoComercial-CompartirIgual 3.0 Chile (CC BY-NC-SA 3.0 CL)
Licencia URL
http://creativecommons.org/licenses/by-nc-sa/3.0/cl/
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Artículos de Revistas