Anatomical variants of the origin of the coronary arteries: a systematic review and meta-analysis of prevalence

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dc.contributor.authorValenzuela Fuenzalida, Juan José
dc.contributor.authorBecerra Rodriguez, Emelyn
dc.contributor.authorQuivira Muñoz, Alonso
dc.contributor.authorBaez Flores, Belén
dc.contributor.authorEscalona Manzo , Catalina
dc.contributor.authorOrellana-Donoso, Mathias
dc.contributor.authorNova Baeza, Pablo
dc.contributor.authorSuazo Santibañez, Alejandra
dc.contributor.authorBruna Mejias, Alejandro
dc.contributor.authorSanchis Gimeno, Juan
dc.contributor.authorGutiérrez Espinoza, Héctor
dc.contributor.authorGranite, Guinivere
dc.date.accessioned2025-03-19T18:45:58Z
dc.date.available2025-03-19T18:45:58Z
dc.date.issued2024-06-24
dc.description.abstractPurpose: The most common anomaly is an anomalous left coronary artery originating from the pulmonary artery. These variants can be different and depend on the location as well as how they present themselves in their anatomical distribution and their symptomatological relationship. For these reasons, this review aims to identify the variants of the coronary artery and how they are associated with different clinical conditions. Methods: The databases Medline, Scopus, Web of Science, Google Scholar, CINAHL, and LILACS were researched until January 2024. Two authors independently performed the search, study selection, and data extraction. Methodological quality was evaluated using an assurance tool for anatomical studies (AQUA). Pooled prevalence was estimated using a random effects model. Results: A total of 39 studies met the established selection criteria. In this study, 21 articles with a total of 578,868 subjects were included in the meta-analysis. The coronary artery origin variant was 1% (CI = 0.8-1.2%). For this third sample, the funnel plot graph showed an important asymmetry, with a p-value of 0.162, which is directly associated with this asymmetry. Conclusions: It is recommended that patients whose diagnosis was made incidentally and in the absence of symptoms undergo periodic controls to prevent future complications, including death. Finally, we believe that further studies could improve the anatomical, embryological, and physiological understanding of this variant in the heart.
dc.identifier.citationDiagnostics, Vol. 14, N°13, 1458 (2024) p. 1-21
dc.identifier.doihttps://doi.org/10.3390/diagnostics14131458
dc.identifier.issne2075-4418
dc.identifier.orcidhttps://orcid.org/0000-0002-1781-062X
dc.identifier.urihttps://hdl.handle.net/20.500.12254/4064
dc.language.isoen
dc.publisherMDPI
dc.rightsAtribución-NoComercial-CompartirIgual 3.0 Chile (CC BY-NC-SA 3.0 CL)
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/cl/
dc.subjectCoronary artery
dc.subjectLeft coronary artery (LCA)
dc.subjectRight coronary artery (RCA)
dc.subjectOrigin anomalous coronary artery
dc.subjectClinical anatomy
dc.subjectAnatomical variation
dc.titleAnatomical variants of the origin of the coronary arteries: a systematic review and meta-analysis of prevalence
dc.typeArticle
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