Effect of supervised resistance training on arm volume, quality of life and physical perfomance among women at high risk for breast cancer-related Lymphedema: A study protocol for a randomized controlled Trial (STRONG-B)

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dc.contributor.authorRamírez-Parada, Karol
dc.contributor.authorLopez-Garzon, Maria
dc.contributor.authorSanchez-Rojel, Cesar
dc.contributor.authorPetric-Guajardo, Militza
dc.contributor.authorAlfaro-Barra, Margarita
dc.contributor.authorFernández-Verdejo, Rodrigo
dc.contributor.authorReyes-Ponce, Alvaro
dc.contributor.authorMerino-Pereira, Gina
dc.contributor.authorCantarero-Villanueva, Irene
dc.date.accessioned2022-03-31T16:04:24Z
dc.date.available2022-03-31T16:04:24Z
dc.date.issued2022-03
dc.description.abstractObjectives: To determine the preventive effects of supervised resistance training on arms volume, quality of life, physical performance, and handgrip strength in Chilean women at high risk for breast cancer-related lymphedema (BCRL) undergoing chemotherapy. Design: Randomized control trial. Participants: One hundred and six women at high risk for breast cancer-related lymphedema aged 18 to 70 years. Interventions: Participants will be randomized into two groups: [a] intervention, who will receive 12 weeks of supervised resistance training (STRONG-B) during adjuvant chemotherapy; and [b] control, who will receive education to promote lymphatic and venous return, maintain range of motion, and promote physical activity. Main Outcome Measures: The primary outcome will be arms volume measured with an optoelectric device (perometer NT1000). Secondary outcomes will be quality of life, handgrip strength, and physical performance. Primary and secondary outcomes will be measured at baseline, just after the intervention, and 3 and 6 months after. Statistical analysis will be performed following intention-to-treat and per-protocol approaches. The treatment effect will be calculated using linear mixed models. Discussion: The STRONG-B will be a tailored supervised resistance training that attempts to prevent or mitigate BCRL in a population that, due to both intrinsic and extrinsic factors, will commonly suffer from BCRL. Clinical Trial Registration: [https://clinicaltrials.gov/ct2/show/NCT04821609], identifier NCT04821609.es
dc.description.sponsorshipThe study is funded by ANID+FONDEF/XVII Concurso Nacional de Proyectos de Investigación y Desarrollo en Salud, Fonis (SA20I0060). This work is part of KR-P’s doctoral work at the Clinical Medicine and Public Health Doctoral Studies of the University of Granada, Spain.es
dc.identifier.citationRam´ırez-Parada K, Lopez-Garzon M, Sa´ nchez-Rojel C, Petric-Guajardo M, Alfaro-Barra M, Fernandez-Verdejo R, Reyes-Ponce A, Merino-Pereira G and Cantarero-Villanueva I (2022) Effect of Supervised Resistance Training on Arm Volume, Quality of Life and Physical Perfomance Among Women at High Risk for Breast Cancer-Related Lymphedema: A Study Protocol for a Randomized Controlled Trial (STRONG-B). Front. Oncol. 12:850564. doi: 10.3389/fonc.2022.850564es
dc.identifier.issn2234-943X
dc.identifier.orcid0000-0002-5948-2281es
dc.identifier.urihttp://hdl.handle.net/20.500.12254/2269
dc.language.isoen_USes
dc.publisherFrontiers Mediaes
dc.relation.ispartofseriesFrontiers in Oncology;12
dc.subject.otherBreast cancer lymphedemaes
dc.subject.otherBreast neoplasmses
dc.subject.otherPhysical therapy specialtyes
dc.subject.otherQuality of lifees
dc.subject.otherResistance traininges
dc.titleEffect of supervised resistance training on arm volume, quality of life and physical perfomance among women at high risk for breast cancer-related Lymphedema: A study protocol for a randomized controlled Trial (STRONG-B)es
dc.typeArtículoes
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