Transient acquired factor XII deficiency associated with moderately severe Covid-19 pneumonia
Fecha
2021-11
Profe guía
Perfil ORCID
Título de la revista
ISSN de la revista
Título del volumen
Editor
Elsevier
ISBN
ISSN
2531-1379
ISSNe
2531-1387
Resumen
The case report demonstrates the importance of investigating alternative causes of a prolonged APTT in patients with Covid-19. Although Covid-19 is associated with thrombotic complications it is possible that immune dys-regulation associated with SARS-CoV-2 may lead to other coagulation factor inhibitors and a hemorrhagic tendency.
Clinical decisions on anticoagulant treatment may be influenced by the APTT and modified in patients with Covid-19. Management of these cases requires the clinical acumen to balance the potential for haemorrhagic and thrombotic complications of SARS-CoV-2 infection. The abnormalidades in the coagulation tests may persist long after clinical remission and resolution of inflammatory markers.
Descripción
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Citación
Hematology, Transfusion and Cell Therapy, Vol. 43, N°4, (2021) p. 515-517
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Licencia
Atribución-NoComercial-CompartirIgual 3.0 Chile (CC BY-NC-SA 3.0 CL)