Transient acquired factor XII deficiency associated with moderately severe Covid-19 pneumonia
Fecha
2021-11
Nota de Acceso
Fecha de embargo
Autores
Murray, Nigel P.
Guzman, Eghon
Del Prado, Monica
Profe guía
Perfil ORCID
Título de la revista
ISSN de la revista
Título del volumen
Editor
Elsevier
ISBN
ISSN
2531-1379
ISSNe
2531-1387
Resumen
The case report demonstrates the importance of investigating alternative causes of a prolonged APTT in patients with Covid-19. Although Covid-19 is associated with thrombotic complications it is possible that immune dys-regulation associated with SARS-CoV-2 may lead to other coagulation factor inhibitors and a hemorrhagic tendency.
Clinical decisions on anticoagulant treatment may be influenced by the APTT and modified in patients with Covid-19. Management of these cases requires the clinical acumen to balance the potential for haemorrhagic and thrombotic complications of SARS-CoV-2 infection. The abnormalidades in the coagulation tests may persist long after clinical remission and resolution of inflammatory markers.
Descripción
Lugar de Publicación
Sponsorship
Citación
Hematology, Transfusion and Cell Therapy, Vol. 43, N°4, (2021) p. 515-517
Palabras clave
Licencia
Atribución-NoComercial-CompartirIgual 3.0 Chile (CC BY-NC-SA 3.0 CL)