Jannas-Vela, SebastianCastro-Sepulveda, Mauricio2024-11-282024-11-282023-02-22En: Ostojic, Sergej M. (edited). Molecular Nutrition and Mitochondria: Metabolic Deficits, Wole-Diet Interventions, and Targeted Nutraceuticals. Elsevier; Academic Press, 2022. pp. 213-224.9780323902564http://hdl.handle.net/20.500.12254/3935It appears that n-3 PUFA supplementation has a minimal effect on mitochondrial biogenesis in humans. However, recent studies suggest a positive effect of n-3 PUFAs on mitochondrial function and dynamics. Further studies are needed to fully understand the mechanism behind these adaptations, mainly focusing on the association between mitochondrial dynamics and mitochondrial function (e.g., bioenergetics). We hypothesize that incorporation of n-3 PUFAs into the mitochondrial membrane favors mitochondrial fusion, leading to improved mitochondrial function and enhanced skeletal muscle health.enAtribución-NoComercial-CompartirIgual 3.0 Chile (CC BY-NC-SA 3.0 CL)MitochondrialMitochondrial dynamicsMitochondrial functionBook chapterhttps://orcid.org/0000-0002-2270-299Xhttps://doi.org/10.1016/C2020-0-02475-8